منابع مشابه
Regulatory T cells in asthma.
Asthma is characterized by T helper cell 2 (Th2) type inflammation, leading to airway hyperresponsiveness and tissue remodeling. Th2 cell-driven inflammation is likely to represent an abnormal response to harmless airborne particles. These reactions are normally suppressed by regulatory T cells, which maintain airway tolerance. The anti-inflammatory cytokine IL-10 is likely to play a central ro...
متن کاملRegulatory T Cells in Allergy and Asthma
The immune system's correct functioning requires a sophisticated balance between responses to continuous microbial challenges and tolerance to harmless antigens, such as self-antigens, food antigens, commensal microbes, allergens, etc. When this equilibrium is altered, it can lead to inflammatory pathologies, tumor growth, autoimmune disorders, and allergy/asthma. The objective of this review i...
متن کاملT Helper Cells Profile and CD4+CD25+Foxp3+Regulatory T Cells in Polycystic Ovary Syndrome
Background: Polycystic ovary syndrome (PCOS) is considered as the most common cause of female infertility that affects 4-10% of women in the reproductive age. Previous studies have shown the role of a balanced immune response in a successful pregnancy and fertility. Objective: To investigate the T helper cells type 1 (Th1) /Th2/Th17/Treg paradigms in peripheral blood of infertile PCOS compared ...
متن کاملRegulatory T Cells in Colorectal Cancer
One of the essential protection mechanisms of immune system is Treg cells which play an important role in maintenance ofimmune homeostasis. However, they may also inhibit immune functions against tumor cells. It has been reported that Treg cellsare increased in patients suffering from different types of cancer. Increased number of Treg cells has been shown in tumor lymphnodes, peripheral blood,...
متن کاملimbalance of peripheral th17 and regulatory t cells in children with allergic rhinitis and bronchial asthma
the purpose of the present study is to investigate the prevalence of th17 and regulatory t (treg) cells in children with allergic rhinitis (ar) accompanying with bronchial asthma (ba).24 children with ar, 22 children with ba, 18 children with ar accompanying with ba,and 20 healthy controls were recruited. the prevalence of peripheral blood th17 and treg cells were determined by flow cytometry. ...
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ژورنال
عنوان ژورنال: Journal of Zhejiang University-SCIENCE B
سال: 2018
ISSN: 1673-1581,1862-1783
DOI: 10.1631/jzus.b1700346